FMF Disease

FMF Disease Symptoms And Treatment

Our today topic is fmf disease.What is fmf disease?And what are the symptoms of fmf disease.Treatments Of fmf disease.

What is FMF?
The familial mediterranean fever, shortly called FMF , is a disease that causes fever and pain in the abdominal region of the lungs and joints.

The FMF is a hereditary disorder seen in people of the Mediterranean, including Jews, Arabs, Italians and Turks, but it can also affect other ethnic groups.

FMF Disease Symptoms And Treatment

Symptoms of FMF Disease
The indication of FMF disease usually begins in childhood. Symptoms last 1-3 days in seizures. Common symptoms include:

Abdominal pain
Chest pain
Painful swollen wrists
Diarrhea followed by constipation
Especially the knees under the knee
Muscle pain
Swollen and tense testicular bag
The patient feels normal between seizures. Sometimes the manifestation can be as little as 1 week, sometimes as a month. The following factors can trigger the disease episodes:


Causes of FMF Disease
FMF is the result of a mutation in the gene that passes from family to family. Gene mutation causes disruptions in the body’s inflammation (inflammation).

In FMF patients the gene mutation is seen in a gland called MEFV. Many mutations in the MEFV gene are directly related to FMF disease. Some mutations lead to very serious conditions, while others can be moderate.

The FMF disease results in an autosomal recessive behavioral consequence of mutation from both the mother and the fetus.

FMF Disease Symptoms And Treatment


Risk Factors
The factors that increase the risk of disease are:

If you have someone with FMF in your family history, the risk of getting sick will increase.
If the origins of origin belong to the Mediterranean region, the risk of developing the disease is increased.
Complications that may occur if FMF disease is not treated include:

– During FMF episodes, the body produces a protein called amyloid A, which is an abnormal protein. When this protein accumulates in the body it can cause organ damage.

– Amyloidosis can cause damage to the kidneys by causing nephrotic syndrome. Nephrotic syndrome occurs when the kidneys filter system is damaged. People with this condition lose protein in high amounts through the urine. The nephrotic system may also cause blood clotting or kidney failure in the kidneys.

– Inflammation caused by FMF disease can cause infertility by affecting the reproductive organs of women.

– FMF patients have inflammation of the joint called arthritis. Most affected joints are affected by knee, ankle and hip joints.

Tests and Diagnostics
The tests and procedures used to diagnose FMF disease are:

Physical Test

The doctor can ask questions about the symptoms and perform a physical test for more information.

FMF Disease Symptoms And Treatment


Family History Review

The doctor will ask if there are any people with FMF in their family history because this genetic mutation can be passed on from family to family.

Blood Tests

Blood tests performed during episodes of sickness show the size of inflammation in the body. Usually white blood cells increase in number to infect with infection.

Genetic Test

Genetic tests reveal whether there is a mutation in FMF disease in the MEFV gene. But genetic tests have not yet developed enough to reveal all the mutations associated with FMF. For this reason, doctors rarely use genetic tests during diagnosis.

Treatment of FMF Disease
There is no remedy for FMF disease yet, but treatment can help prevent the indication. The following medications are used to check for signs of FMF:

Kolsişin (saffron)

This medication is taken in the form of a pill and helps to reduce inflammations in the body and prevent seizures. It is very important to get the most appropriate dose. Some people may take 1 dose per day, while others may receive less or more frequent doses. Potential side effects include diarrhea, weakness in the muscles and numbness in hands and feet.

Potassium is potentially toxic, so it is important not to use overdose. It improves symptoms of 90-95% of colonic patients.

FMF Disease Symptoms And Treatment


Other Medicines

Patients who are not able to control the symptoms with colistin are attempted to check for signs of infection using other anti-inflammatory drugs. For this reason, these drugs can be considered experimentally. The most common cause in patients not responding to colic is digestive disorders.

Huntington’s Disease

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