Addison's Disease

Addison’s Disease Symptoms And Treatment

Our today topic is addison’s disease symptoms and treatment.Former United States President John F. Kennedy , who was killed in 1963 as an aftermath of an assassination, had the disease Addison.

What is Addison’s Disease?
Addison’s disease is the result of damage to the adrenal cortex and the absence of steroid hormones called cortisol and aldosterone in the adrenal glands.

Addison’s Disease Symptoms And Treatment

Low Cortisol and Aldosterone
Cortisol regulates the body’s reactions to stressful situations. It also regulates the use of carbohydrates, protein and fat in the body and helps the blood pressure maintain cardiovascular function and control inflammations. Aldosterone helps regulate sodium and potassium minerals in the body, assists salt and water balance in the kidneys, and helps control blood volume and blood pressure. In the absence of aldosterone hormone, kidneys can not provide water and salt balance and blood pressure falls.

Addison’s disease is a rare disease seen in every 100,000 people 1 and can be seen in men and women of all ages. People with Addison’s disease can continue their normal life as long as they take their medication.

Addison’s Disease Symptoms And Treatment

Causes of Addison’s Disease
There are two types of Addison’s disease: primary renal insufficiency and secondary renal insufficiency. For accurate and complete treatment your doctor will determine what kind of disease it has.

Reasons for Primary Abnormal Bowel Failure

Addison’s disease often occurs when the immune system attacks the adrenal glands. For this reason, it is an autoimmune disease. In an autoimmune disease, the body’s immune system mixes an organ or region with a virus, bacteria, or external aggressor.

Addison’s Disease Symptoms And Treatment

Other Predominant Causes

Taking glucocorticoids to the body for long periods
Infection in the body can cause Addison’s disease. Fungal infections may also contribute to the disease.
Uncontrolled growth of cancer and tumors
Blood coagulants used to control clotting can over time affect the adrenal glands.
Reasons for Secondary Abnormal Bowel Failure

Addison’s Disease Symptoms And Treatment

Secondary adrenal insufficiency occurs when the adrenal glands can not produce adrenocorticotropic hormone (ACTH). ACTH sends a signal to the adrenal gland that it will release the hormone.
Secondary adrenal insufficiency can also be seen if corticosteroid medications, which should be used with a doctor’s recommendation, are not used.
In addition, cancer patients and tuberculosis patients are at risk of getting addison disease.

Addison’s Disease Symptoms And Treatment

Addison’s Disease Symptoms
chronic fatigue and muscle weakness
increased skin pigmentation (skin becomes darker)
weight loss, reduced appetite and difficulty in digestion
decrease in heart rate and blood pressure
low blood sugar
fainting
pain in the oral area
salt demand
nausea
vomiting
nervousness and depression
stress in struggle with stress
increased sensitivity to heat and cold
Some of these symptoms may also point to other disturbances from Addison’s disease. Because the symptoms of Addison’s disease go too heavily and the symptoms quickly worsen when a physically stressful condition such as another disease, surgery or accident appears. This is called Addison syndrome. That’s why people with Addison’s disease know they are sick when they see 1 out of 4 people with this syndrome. Addison syndrome should be treated medically urgently, otherwise it can be fatal.

Addison’s Disease Symptoms And Treatment

Symptoms of Addison’s syndrome include:

Severe pain that develops suddenly in the belly, in the abdomen or on the stomach
Excessive fluid loss following severe vomiting and diarrhea
Rapidly falling blood pressure
Loss of consciousness
The kidneys become unable to perform their duty
Diagnosis of the disease
The doctor then applies a physical test after asking for signs and symptoms. In addition, potassium and sodium levels are measured. In other tests, hormone levels are determined visually.

Addison’s Disease Symptoms And Treatment

Treatment of Addison’s Disease
Since Addison’s disease is caused by a deficiency of hormones produced from the adrenal glands, treatment of the disease is performed by supplementing these missing hormones. This is done by taking one or two hydrocortisone steroid hormone tablets per day depending on the condition or severity of the disease. When necessary, aldosterone is replaced with a synthetic steroid called fludrocortisone acetate, which is taken once a day as a tablet. These medicines can sometimes be increased in dose due to reasons such as stress, infection, surgery or disability by doctor intervention.

Addison’s Disease Symptoms And Treatment

Drug treatments in Addison’s disease are always successful. Patients who continue their treatments regularly continue their normal lives without any problems. But to prevent the forgetting of medication clocks, the bracelets used for signaling medical purposes and patient ID cards should be used for emergencies because Addison’s disease is a life-long chronic disease. It can be dangerous to miss even a single dose.

In patients with Addison syndrome or a crisis, the patient is given a rapid injection of salt, liquid and glucocorticoid hormones prescribed by the doctor.

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